GeneX
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What is it?
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GeneX is one of the three applications of MGX( Fall 2004 team at UMB) . It was originally developed by Fall 2003 team at UMB and is being re-developed to enhance the functionalities and improve the existing features.
GeneX is a simulation that provides an opportunity for beginning students to understand the “central dogma” of molecular biology. The process by which information is extracted from the nucleotide sequence of a gene and used to make a protein is essentially the same for all living things on Earth and is described by the grandly named central dogma of molecular biology. The goal of this application is to help students visualize this very important concept. GenExplorer provides a graphically interactive environment for the students to interpret the information encoded in a DNA sequence.
In order to interpret the information in a DNA sequence, the students input the sequence into GeneX. The program then starts scanning the sequence for promoter and terminator and graphically displays every step of gene expression (transcription, splicing and translation) from a nucleotide sequence into protein. GeneX provides students with the freedom to mutate a nucleotide sequence and track the effect of mutation down to the protein sequence. Students would also be able to visually interpret the involvement of a nucleotide base or a protein in each step of the entire process of gene expression.
What are the license terms for using GeneX?
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This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2
of the License, or (at your option) any later version.
This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
GNU General Public License for more details.
Downloads and home page
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The homepage is:
Downloads of the current alpha release are available at:
under GeneX column
How do I install this application?
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Please see the install.txt notes under GeneX column.
Contact us:
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Feel free to send us feedback by email mgx@cs.umb.edu
Note:
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This is a beta release and we are still working to improve the application by removing bugs.